The following clinical evaluations are important for patients with Alström Syndrome. 

 

• Assessment of vision, ERG during childhood
• Audiometry yearly
• Height/weight, BMI
• Heart function tests, ECG and echocardiography yearly or every 6 months, if indicated
• Fasting glucose, insulin
• Blood pressure
• Liver ultrasonography
• Serum chemistry for
  • renal function (creatinine, uric acid, creatinine-clearance, BUN)
  • liver function (ALT, AST, GGT)
  • lipid panel (cholesterol, triglycerides)
• Thyroid function (TSH, T4); look for sub-clinical hypothyroidism
• Gastrointestinal function, esophageal reflux
• Gonadal function (LH, FSH, testosterone)
• Pulmonary function tests
• Assess any urological dysfunction
• Skeletal abnormalities, scoliosis, kyphosis
• Neurological evaluation (absense seizures, ataxia)

Additional monitoring recommendations 

Guidelines and Rationale for Treatment of Endocrinological Disorders and Diabetes Occurring in Alström Syndrome