Mouse models for Alström Syndrome exhibit most of the characteristics seen in human patients with Alström Syndrome, including vision and hearing impairment and obesity.
Mouse models for Alström Syndrome exhibit most of the characteristics seen in human patients
with Alström Syndrome, including vision and hearing impairment and obesity.
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Larter CZ, Yeh MM, Haigh WG, Van Rooyen DM, Brooling J, Heydet D, Nolan CJ, Teoh NC, Farrell GC. Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease.
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Larter CZ, Yeh MM, Van Rooyen DM, Brooling J, Ghatora K, Farrell GC.
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Arsov T, Silva DG, O’Bryan MK, Sainsbury A, Lee NJ, Kennedy C, Manji SS, Nelms K, Liu C, Vinuesa CG, de Kretser DM, Goodnow CC, Petrovsky N (2006): Fat aussie–a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis. Mol Endocrinol. 20(7):1610-22.
Arsov T, Larter CZ, Nolan CJ, Petrovsky N, Goodnow CC, Teoh NC, Yeh MM, Farrell GC. (2006): Adaptive failure to high-fat diet characterizes steatohepatitis in Alms1 mutant mice. Biochem Biophys Res Commun. 342(4):1152-9.
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